Background: Many plant secondary metabolites (PSMs) were shown to intercalate into DNA helix or interact with DNA grooves. This may influence histone-DNA interactions changeing chromatin structure and genome functioning. Methods: Nucleosome stability and linker histone H1. https://www.markbroyard.com/amazing-price-color-touch-7-97-medium-blonde-cendre-brown-online-now-mega-choice/