Inadequate/Intensive Metabolizers, CYP2D6 The development on the active metabolite, M1, is mediated by CYP2D6, a polymorphic enzyme. Around 7% with the inhabitants has minimized activity of your CYP2D6 isoenzyme of cytochrome P450 metabolizing enzyme process. These persons are “very poor metabolizers” of debrisoquine, dextromethorphan and tricyclic antidepressants, amid other medicine. https://johnj764xgo4.blogrenanda.com/profile