This serves as a germinal centre survival signal for autoreactive B-cells. Soon after migration into the mantle zone, autoreactive B cells involve further more survival signals from autoreactive helper T cells, which encourage the maturation of autoantibody-creating plasma cells and B memory cells. Micrograph of a section of human https://felixqbcoq.fireblogz.com/69893797/lupus-diagnosis-an-overview